Research
- Burns EE, Keith BK, Refai MY, Bothner B, Dyer WE. Constitutive redox and phosphoproteome changes in multiple herbicide resistant Avena fatua L. are similar to those of systemic acquired resistance and systemic acquired acclimation. J Plant Physiol. 2017 Nov 20;220:105-114. doi: 10.1016/j.jplph.2017.11.004. [Epub ahead of print]PMID:29169105
- Hamerly T, Everett JA, Paris N, Fisher ST, Karunamurthy A, James GA, Rumbaugh KP, Rhoads DD, Bothner B. Detection of Pseudomonas aeruginosa biomarkers from thermally injured mice in situ using imaging mass spectrometry. Anal Biochem. 2017 Dec 15;539:144-148. doi: 10.1016/j.ab.2017.10.012. Epub 2017 Oct 28. PMID: 29107579
- Evan Erp PBG, Patterson A, Kant R, Berry L, Golden SM, Forsman BL, Carter J, Jackson RN, Bothner B, Wiedenheft B. Conformational Dynamics of DNA Binding and Cas3 Recruitment by the CRISPR RNA-guide Cascade Complex. ACS Chem Biol. 2017 Oct 16. doi: 10.1021/acschembio.7b00649. [Epub ahead of print] PMID: 29035497
- Berry L, Poudel S, Tokmina-Lukaszewska M, Colman DR, Nguyen DMN, Schut GJ, Adams MWW, Peters JW, Boyd ES, Bothner B. H/D exchange mass spectrometry and statistical coupling analysis reveal a role for allostery in a ferredoxin-dependent bifurcating transhydrogenase catalytic cycle. Biochim Biophys Acta. 2018 Jan;1862(1):9-17. doi: 10.1016/j.bbagen.2017.10.002. Epub 2017 Oct 6. PMID: 28993252
- Bennett A, Patel S, Mietzsch M, Jose A, Lins-Austin B, Yu JC, Bothner B, McKenna R, Agbandje-McKenna M. Thermal Stability as a Determinant of AAV Serotype Identity. Mol Ther Methods Clin Dev. 2017 Jul 24;6:171-182. doi: 10.1016/j.omtm.2017.07.003. eCollection 2017 Sep 15. PMID: 28828392
- Pence N, Tokmina-Lukaszewska M, Yang ZY, Ledbetter RN, Seefeldt LC, Bothner B, Peters JW. Unraveling the interactions of the physiological reductant flavodoxin with the different conformations of the Fe protein in the nitrogenase cycle. J Biol Chem. 2017 Sep 22;292(38):15661-15669. doi: 10.1074/jbc.M117.801548. Epub 2017 Aug 7. PMID:28784660
- Heinemann J, Noon B, Willems D, Budeski K, Bothner B. Analysis of Raw Biofluids by Mass Spectrometry Using Microfluidic Diffusion-Based Separation. Anal Methods. 2017 Jan 21;9(3):385-392. doi: 10.1039/C6AY02827F. Epub 2016 Dec 6.PMID: 28713441
- Nguyen DMN, Schut GJ, Zadvornyy OA, Tokmina-Lukaszewska M, Poudel S, Lipscomb GL, Adams LA, Dinsmore JT, Nixon WJ, Boyd ES, Bothner B, Peters JW, Adams MWW. Two functionally distinct NADP+-dependent ferredoxin oxidoreductases maintain the primary redox balance of Pyrococcus furiosus. J Biol Chem. 2017 Sep 1;292(35):14603-14616. doi: 10.1074/jbc.M117.794172. Epub 2017 Jul 13. PMID:28705933
- Ledbetter RN, Garcia Costas AM, Lubner CE, Mulder DW, Tokmina-Lukaszewska M, Artz JH, Patterson A, Magnuson TS, Jay ZJ, Duan HD, Miller J, Plunkett MH, Hoben JP, Barney BM, Carlson RP, Miller AF, Bothner B, King PW, Peters JW, Seefeldt LC. The Electron Bifurcating FixABCX Protein Complex from Azotobacter vinelandii: Generation of Low-Potential Reducing Equivalents for Nitrogenase Catalysis. Biochemistry. 2017 Aug 15;56(32):4177-4190. doi: 10.1021/acs.biochem.7b00389. Epub 2017 Aug 3. PMID: 28704608
- Rawle RA, Hamerly T, Tripet BP, Giannone RJ, Wurch L, Hettich RL, Podar M, Copié V, Bothner B. Multi-omics analysis provides insight to the Ignicoccus hospitalis-Nanoarchaeum equitans association. Biochim Biophys Acta. 2017 Sep;1861(9):2218-2227. doi: 10.1016/j.bbagen.2017.06.001. Epub 2017 Jun 4. PMID: 28591626
- Keith BK, Burns EE, Bothner B, Carey CC, Mazurie AJ, Hilmer JK, Biyiklioglu S, Budak H, Dyer WE.Intensive herbicide use has selected for constitutively elevated levels of stress-responsive mRNAs and proteins in multiple herbicide-resistant Avena fatua L. Pest Manag Sci. 2017 Nov;73(11):2267-2281. doi: 10.1002/ps.4605. Epub 2017 Aug 18. PMID: 28485049
- Lubner CE, Jennings DP, Mulder DW, Schut GJ, Zadvornyy OA, Hoben JP, Tokmina-Lukaszewska M, Berry L, Nguyen DM, Lipscomb GL, Bothner B, Jones AK, Miller AF, King PW, Adams MWW, Peters JW. Mechanistic insights into energy conservation by flavin-based electron bifurcation. Nat Chem Biol. 2017 Jun;13(6):655-659. doi: 10.1038/nchembio.2348. Epub 2017 Apr 10. PMID: 28394885
- Xia N, Fang F, Zhang P, Cui J, Tep-Cullison C, Hamerley T, Lee HJ, Palmer T, Bothner B, Lee JH, Pera RR. A Knockin Reporter Allows Purification and Characterization of mDA Neurons from Heterogeneous Populations. Cell Rep. 2017 Mar 7;18(10):2533-2546. doi: 10.1016/j.celrep.2017.02.023.PMID: 28273465
- Kant R, Zeng B, Thomas CJ, Bothner B, Sprang SR. Elife. Ric-8A, a G protein chaperone with nucleotide exchange activity induces long-range secondary structure changes in Gα. 2016 Dec 23;5. pii: e19238. doi: 10.7554/eLife.19238. PMID:28008853
- Tokmina-Lukaszewska M, Shi Z, Tripet B, McDermott TR, Copié V, Bothner B, Wang G. Metabolic response of Agrobacterium tumefaciens 5A to arsenite. Environ Microbiol. 2017 Feb;19(2):710-721. doi: 10.1111/1462-2920.13615. Epub 2017 Jan 23.PMID: 27871140
- Llauró A, Guerra P, Kant R, Bothner B, Verdaguer N, de Pablo PJ. Decrease in pH destabilizes individual vault nanocages by weakening the inter-protein lateral interaction. Sci Rep. 2016 Oct 14;6:34143. doi: 10.1038/srep34143. PMID: 27739422
- Kuznedelov K, Mekler V, Lemak S, Tokmina-Lukaszewska M, Datsenko KA, Jain I, Savitskaya E, Mallon J, Shmakov S, Bothner B, Bailey S, Yakunin AF, Severinov K, Semenova E. Altered stoichiometry Escherichia coli Cascade complexes with shortened CRISPR RNA spacers are capable of interference and primed adaptation. Nucleic Acids Res. 2016 Dec 15;44(22):10849-10861. Epub 2016 Oct 13. PMID: 27738137
- Mason KE, Hilmer JK, Maaty WS, Reeves BD, Grieco PA, Bothner B, Fischer AM. Proteomic comparison of near-isogenic barley (Hordeum vulgare L.) germplasm differing in the allelic state of a major senescence QTL identifies numerous proteins involved in plant pathogen defense. Plant Physiol Biochem. 2016 Dec;109:114-127. doi: 10.1016/j.plaphy.2016.09.008. Epub 2016 Sep 14. PMID: 27665045
- Parker GJ, Leppert T, Anex DS, Hilmer JK, Matsunami N, Baird L, Stevens J, Parsawar K, Durbin-Johnson BP, Rocke DM, Nelson C, Fairbanks DJ, Wilson AS, Rice RH, Woodward SR, Bothner B, Hart BR, Leppert M. Demonstration of Protein-Based Human Identification Using the Hair Shaft Proteome. PLoS One. 2016 Sep 7;11(9):e0160653. doi: 10.1371/journal.pone.0160653. eCollection 2016. PMID: 27603779
- Yang ZY, Ledbetter R, Shaw S, Pence N, Tokmina-Lukaszewska M, Eilers B, Guo Q, Pokhrel N, Cash VL, Dean DR, Antony E, Bothner B, Peters JW, Seefeldt LC. Evidence That the Pi Release Event Is the Rate-Limiting Step in the Nitrogenase Catalytic Cycle. Biochemistry. 2016 Jul 5;55(26):3625-35. doi: 10.1021/acs.biochem.6b00421. Epub 2016 Jun 22. PMID: 27295169
- Poudel S, Tokmina-Lukaszewska M, Colman DR, Refai M, Schut GJ, King PW, Maness PC, Adams MW, Peters JW, Bothner B, Boyd ES. Unification of [FeFe]-hydrogenases into three structural and functional groups. Biochim Biophys Acta. 2016 Sep;1860(9):1910-21. doi: 10.1016/j.bbagen.2016.05.034. Epub 2016 May 27. PMID: 27241847